Product: Clenbuterol Chlamydem
Manufacture: Elite Pharm
Pack: 100 tablets
Steroid cycle: cutting
Active substance: Clenbuterol hydrochloride
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Clenbuterol - is one of the most known and effective medications.
The mass distribution among athletes was in the late 80s early 90s of last century.
In 1992, the drug was included in the list of doping agents and professional sport since then practically disappeared.
However, today, it is widely used by bodybuilders, amateurs, they need not worry about the results going doping control.
The study was conducted in 2010, it found that a synergistic effect when combined with anabolic steroids is present, and therefore, makes sense to include the drug at the end of the course of receiving anabolic steroids.
In 2012, another unique feature of the product was discovered - may block the mechanisms of muscle atrophy.
Human study was conducted in 2015, which confirmed the effectiveness of the drug. The optimal dose of admission, protein synthesis was observed significantly improved guest stimulates anabolism, they have been identified with complications in the manifestations of conditions or side effects of a person.
It is a beta-2 agonist clenbuterol acts as a fat burner, binding to beta-receptor type 2 in adipose and muscle tissue of the human body. Once the receptor binds clenbuterol, a cascade of biochemical reactions that lead to an increase in cAMP synthesis (cyclic adenosine monophosphate) starts. cAMP in turn activates enzymes that mobilize fatty acids from adipocytes (fat tissue cells).
The action of clenbuterol on beta-2 adrenergic presynaptic membrane power release noradrenaline and adrenaline, which possess potent fat-burning effect receptors. Clenbuterol increases the basal metabolic rate by 20-30% of the initial value.
Clenbuterol inhibits the activity of lipoprotein lipase, it becomes impossible resulting in the deposition of fat in adipose tissue. Acting beta-2-adrenergic central nervous system receptors, the drug increases the secretion of thyroid hormones - natural fat burner body.
A unique feature of clenbuterol is that it is not only a powerful fat burner, but also has a strong anti-catabolic effect, protecting muscles from breaking down, which is very important for weight loss and drying bodybuilding. Studies have found that the anti-catabolic effect of the drug due to blockage of the dependent ubiquitin-proteasome proteolysis and Ca2 +.
Unlike catabolic activity normally associated with the protein function activation of the sympathetic nervous system CRTC / CREB skeletal muscle of transgenic mice leads to an increase of anabolic processes and increased protein synthesis. Therefore, in animals overexpressing CRTC2 myofibers increased cross sectional area, increases the content of triglycerides and intramuscular glycogen content. In addition, there is a significant increase in power rates.
The average duration of the reception rate is about 2 weeks. Then in the human body it is a process of getting used to and the effectiveness of the drug is further reduced significantly.
Therefore, it is important to pause briefly - also about 2 weeks, during which it is desirable to take these drugs, such as ketotifen. Why is this medicine? Because otherwise, the rest time of the drug should be increased significantly. Increasing the break, you risk losing the effects of the reception. The ketotifen, get a body, it acts mainly on the speedy recovery of the body after taking steroids, and their willingness to start new courses.
The need for such a break in making the drug has been shown in the first 90 - IES. The researchers found that desensitization of adrenergic beta-developed by receptor phosphorylation, and other biochemical level modifications second messengers (kinases, protein G-, and others.) Receptors. In updating these structures need a certain period of several days to several weeks.
The main positive effects of taking the drug are drying up human muscle tissue, burn fat in the body of an athlete, activation of mental processes, loss of appetite, anti-catabolic effects, anabolic effects.
The low incidence of adverse events (practice shows that irreversible side effects is almost totally absent) and a wide range of positive effects of clenbuterol make it one of the best fat burners bodybuilding.
In case of violation of the rules of taking the medication or a significant excess of the permitted dose can manifestation of side effects such as improved sweating, nausea, diarrhea, headache, increased blood pressure.
The drug belongs to a group of substances that can and should be combined with other useful steroid to increase the effect and reduce the risk of side effects.
For adult men, the optimal dose is 120 micrograms reception per day.
For women, the dose is slightly smaller - about 80 mg.
The drug is often combined with a course, T3, tiroxifeno, ketotifen.
Is important to remember that in the case of the preparation in combination with other steroids course, the dose should be reduced significantly - up to 20 mg per day.
The product is ideal for maintaining constant muscle tone, it is a good fat burner has a strong anabolic effect.
When you receive it with such drugs as tiroxifeno, ketotifen not only increases the beneficial properties of the drug, but also significantly reduces the risk of negative side effects.
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